{"id":1066,"date":"2026-01-20T15:13:05","date_gmt":"2026-01-20T23:13:05","guid":{"rendered":"https:\/\/cloudbreaktstg.wpenginepowered.com\/?page_id=1066"},"modified":"2026-01-21T07:34:22","modified_gmt":"2026-01-21T15:34:22","slug":"technology","status":"publish","type":"page","link":"https:\/\/cloudbreakpharma.com\/zh\/technology\/","title":{"rendered":"Technology"},"content":{"rendered":"
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Technology<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Innovative drug therapies to treat ophthalmic diseases<\/strong><\/span><\/h2>

Cloudbreak Pharma has formulated a potent multi-kinase inhibitor to block angiogenesis (development of new blood vessels) and fibrosis (formation of excess fibrous connective tissue) into a topical eye drop to treat anterior segment ophthalmic diseases.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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MULTIKINASE INHIBITOR (MKI)<\/strong><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Our lead technology, Multi-Kinase Inhibitor (MKI)<\/strong>, is de-risked with human clinical results and uniquely suitable for both front-of-eye and back-of-eye diseases. We formulated a potent multi-kinase inhibitor which can block VEGFR (1-3), PDGFR (,), FGFR (1-3) into a topical eye drop to treat pterygium, pinguecula, glaucoma filtration surgery, and adjunct therapy for cornea transplant surgery following 505b(2) regulatory pathway.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFirst to Enter a Potential $1 Billion Opportunity\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tThere are currently no approved drug therapies that address hyperemia and the pterygium lesion\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tMay delay or eliminate need for surgery\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tPharmacologically targeting the angiogenic and fibrovascular pathogenesis of pterygium with promising clinical trial results\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\tIn clinical studies, no systemic effects and ocular AEs were mild and transient; may be used safely well beyond duration limits for corticosteroids\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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SFA+ PLATFORM<\/b><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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Cloudbreak\u2019s proprietary\u00a0SFA+<\/strong>\u00a0platform is a semi\u2011fluorinated alkane\u2013based, non\u2011aqueous delivery system with novel moieties that enables comfortable, multi\u2011dose, preservative\u2011free eye drops with long shelf life, providing a stable formulation option for otherwise \u201cunstable\u201d drugs and creating multiple new ophthalmic product opportunities through improved safety, comfort, and innovative life\u2011cycle management.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tFirst to Enter a Potential $1 Billion Opportunity\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tThere are currently no approved drug therapies that address the basis of the pinguecula lesion\n\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tOnly option that is disease-modifying\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tSurgery is not typically an option; CBT-004 has demonstrated sustained effect after dosing is stopped unlike off-label corticosteroids\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t

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\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDesirable safety profile versus off-label options\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/h3>\n\t\t\t\t\n\t\t\t\t\t\t\t\t\t

\n\t\t\t\t\t\tIn clinical studies, no systemic effects and ocular AEs were mild and transient; no treatment-limiting side effects (unlike corticosteroids)\t\t\t\t\t<\/p>\n\t\t\t\t\n\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Technology Innovative drug therapies to treat ophthalmic diseases Cloudbreak Pharma has formulated a potent multi-kinase inhibitor to block angiogenesis (development of new blood vessels) and fibrosis (formation of excess fibrous connective tissue) into a topical eye drop to treat anterior segment ophthalmic diseases. MULTIKINASE INHIBITOR (MKI) Our lead technology, Multi-Kinase Inhibitor (MKI), is de-risked with […]<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1066","page","type-page","status-publish","hentry"],"yoast_head":"\nTechnology - Cloudbreak Pharma, Inc.<\/title>\n<meta name=\"description\" content=\"Unmet needs in pterygium management? 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