{"id":772,"date":"2024-07-18T02:43:34","date_gmt":"2024-07-18T09:43:34","guid":{"rendered":"https:\/\/cloudbreakpharma.com\/?page_id=772"},"modified":"2026-06-05T12:07:34","modified_gmt":"2026-06-05T19:07:34","slug":"cbt-004-pinguecula-eye-drop","status":"publish","type":"page","link":"https:\/\/cloudbreakpharma.com\/zh\/pipeline\/cbt-004-pinguecula-eye-drop\/","title":{"rendered":"CBT-004"},"content":{"rendered":"<div data-elementor-type=\"wp-page\" data-elementor-id=\"772\" class=\"elementor elementor-772\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-7caed69 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"7caed69\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-8a28788\" data-id=\"8a28788\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-af8b56b elementor-widget elementor-widget-heading\" data-id=\"af8b56b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">CBT-004<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-63a1b20 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"63a1b20\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-34d54fa\" data-id=\"34d54fa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a085139 elementor-widget elementor-widget-heading\" data-id=\"a085139\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u4e00\u79cd\u9488\u5bf9\u7ffc\u72b6\u80ec\u8089\u60a3\u8005\u7684\u6f5c\u5728\u9996\u521b\u7597\u6cd5<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8222acf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8222acf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a1611c1\" data-id=\"a1611c1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0e32d05 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"0e32d05\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span data-olk-copy-source=\"MessageBody\">CBT-004\u9002\u7528\u4e8e\u8840\u7ba1\u5316\u7684\u7751\u88c2\u6591\u3002 \u7751\u88c2\u6591\u662f\u4e00\u79cd\u5706\u5f62\u3001\u6de1\u9ec4\u8272\u3001\u9686\u8d77\u7684\u7ec4\u7ec7\uff0c\u5f62\u6210\u4e8e\u90bb\u8fd1\u89d2\u819c\u7684\u7ed3\u819c\u4e0a\u3002\u7d2f\u79ef\u7d2b\u5916\u7ebf\u66b4\u9732\u662f\u9020\u6210\u7751\u88c2\u6591\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u7d2b\u5916\u7ebf\u8bf1\u5bfc\u7684\u57fa\u56e0\u7a81\u53d8\u53ef\u80fd\u4f1a\u4fc3\u8fdb\u7751\u88c2\u6591\u75c5\u53d8\u7ec6\u80de\u7684\u5f02\u5e38\u751f\u957f\u3002\u4e00\u822c\u6765\u8bf4\uff0c\u65e0\u75c7\u72b6\u7684\u7751\u88c2\u6591\u4e0d\u9700\u8981\u6cbb\u7597\uff0c\u4f46\u5176\u6de1\u9ec4\u8272\u548c\u51f8\u8d77\u7684\u8f6e\u5ed3\u53ef\u80fd\u4f1a\u5bfc\u81f4\u673a\u68b0\u6027\u6216\u4e0d\u826f\u7684\u6cea\u819c\u5f15\u8d77\u7684\u773c\u8868\u523a\u6fc0\u3002\u5f53\u75c5\u53d8\u51fa\u73b0\u8840\u7ba1\u5316\u548c\/\u6216\u53d1\u708e\u65f6\uff0c\u53ef\u80fd\u4f1a\u5bfc\u81f4\u773c\u90e8\u5145\u8840\u3001\u4e0d\u9002\u3001\u75bc\u75db\u3001\u5f02\u7269\u611f\u3001\u6d41\u6cea\u548c\u7619\u75d2\u7b49\u75c7\u72b6\u3002 \u8840\u7ba1\u5316\u8fc7\u7a0b\u4f9d\u8d56\u4e8e\u8840\u7ba1\u5185\u76ae\u751f\u957f\u56e0\u5b50\uff08VEGF\uff09\u9014\u5f84\u3002\u76ee\u524d\u8fd8\u6ca1\u6709FDA\u6279\u51c6\u7684\u9488\u5bf9\u8840\u7ba1\u5316\u7751\u88c2\u6591\u9002\u5e94\u75c7\u7684\u6cbb\u7597\u65b9\u6cd5\u3002<\/span><\/p><p>CBT-004\u662f\u4e00\u79cd\u6709\u6548\u7684 VEGF \u53d7\u4f53\u6291\u5236\u5242\uff0c\u5177\u6709\u6781\u9ad8\u7684\u6548\u529b\u3002CBT-004\u6cbb\u7597\u8840\u7ba1\u5316\u7751\u88c2\u6591\u7684\u673a\u5236\u662f\u901a\u8fc7\u963b\u65adVEGF\u4fe1\u53f7\u6765\u51cf\u5c11\u5f02\u5e38\u8840\u7ba1\u3002\u6b64\u5916\uff0cCBT-004 \u8fd8\u6291\u5236\u8d1f\u8d23\u8840\u7ba1\u7ef4\u62a4\u7684\u8840\u5c0f\u677f\u884d\u751f\u751f\u957f\u56e0\u5b50\u53d7\u4f53 (PDGFR)\u3002\u901a\u8fc7\u6291\u5236\u8fd9\u4e9b\u8840\u7ba1\u751f\u6210\u751f\u957f\u56e0\u5b50\uff0cCBT-004\u6709\u53ef\u80fd\u963b\u6b62\u6216\u9006\u8f6c\u7751\u88c2\u6591\u75c5\u53d8\u7684\u8fdb\u5c55\u3002<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f8af94 elementor-widget elementor-widget-button\" data-id=\"5f8af94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"\/zh\/our-focus\/pinguecula\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u7751\u88c2\u6591<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"<p>CBT-004 A potential first-in-class treatment for patients with pinguecula CBT-004 is being developed to treat vascularized pinguecula. Pinguecula is a round, yellowish, elevated tissue that develops on the conjunctiva adjacent to the cornea. Cumulative exposure to UV light is the main cause of pinguecula and UV-induced mutations of the gene may promote abnormal cell growth [&hellip;]<\/p>\n","protected":false},"author":12,"featured_media":0,"parent":48,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-772","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/pages\/772","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/comments?post=772"}],"version-history":[{"count":0,"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/pages\/772\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/pages\/48"}],"wp:attachment":[{"href":"https:\/\/cloudbreakpharma.com\/zh\/wp-json\/wp\/v2\/media?parent=772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}