{"id":1183,"date":"2026-02-11T10:27:22","date_gmt":"2026-02-11T18:27:22","guid":{"rendered":"https:\/\/cloudbreaktstg.wpenginepowered.com\/?page_id=1183"},"modified":"2026-04-02T13:48:14","modified_gmt":"2026-04-02T20:48:14","slug":"pinguecula-therapy","status":"publish","type":"page","link":"https:\/\/cloudbreakpharma.com\/zh_hk\/our-focus\/pinguecula-therapy\/","title":{"rendered":"Pinguecula Therapy"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1183\" class=\"elementor elementor-1183\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-26c5ad8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"26c5ad8\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-243e92d\" data-id=\"243e92d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0e5adc3 elementor-widget elementor-widget-text-editor\" data-id=\"0e5adc3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h1 style=\"text-align: center;\"><strong><span style=\"color: #ffffff;\">First Pharmacologic Approach to Target Pinguecula\u2019s Root Cause<\/span><\/strong><\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d7ef27e elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d7ef27e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-5d83e73\" data-id=\"5d83e73\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b1f1d5 elementor-widget elementor-widget-text-editor\" data-id=\"1b1f1d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><span style=\"color: #ffffff;\"><strong>Cloudbreak Pharma<\/strong> is pioneering the first FDA-approvable pharmaceutical treatment for pinguecula \u2014 a condition affecting over 1 billion people worldwide with no approved pharmacological options. Our lead program, <strong>CBT-004<\/strong>, is a proprietary <strong>Multi-Kinase Inhibitor (MKI)<\/strong> eye drop designed to simultaneously target the multiple signaling pathways that drive the abnormal fibrovascular changes of pinguecula, rather than only targeting symptoms.<\/span><\/h3>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-4abb5d0\" data-id=\"4abb5d0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e19e298 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"e19e298\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"800\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-1024x1024.png\" class=\"attachment-large size-large wp-image-1315\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-1024x1024.png 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-300x300.png 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-150x150.png 150w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-768x768.png 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-1536x1536.png 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper-12x12.png 12w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/03\/PG-eye-dropper.png 1688w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3ac697c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3ac697c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3f9c0a9\" data-id=\"3f9c0a9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-38f3983 elementor-widget elementor-widget-spacer\" data-id=\"38f3983\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1c6fb63 elementor-widget elementor-widget-text-editor\" data-id=\"1c6fb63\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><span style=\"color: #375e6f;\"><strong>Multi-Kinase Inhibitor Platform<\/strong><\/span><\/h2><h4 style=\"text-align: center;\">TARGETING THE FULL DISEASE CASCADE, NOT JUST ONE PATHWAY<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58cd723 elementor-widget elementor-widget-text-editor\" data-id=\"58cd723\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center;\">Current management of pinguecula is aimed at easing symptoms and controlling surface inflammation rather than eliminating the underlying degenerative change. Lubricating drops, anti-inflammatory medications, and environmental modifications can reduce irritation, but relief is often incomplete and temporary, and the visible lesion typically remains. In more bothersome cases, patients may still struggle with redness, discomfort, or contact lens intolerance, and only a very limited subset of patients are offered surgery for persistent inflammation or cosmetic concern, underscoring the need for better, targeted therapies.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-eb5b958 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"eb5b958\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/cloudbreakpharma.com\/technology\/mki\/\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn more about MKI's<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afeaad8 elementor-widget elementor-widget-spacer\" data-id=\"afeaad8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a84bc26 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a84bc26\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fa3004c\" data-id=\"fa3004c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7d6fb55 elementor-widget elementor-widget-spacer\" data-id=\"7d6fb55\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cf9617a elementor-widget elementor-widget-text-editor\" data-id=\"cf9617a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>How Pinguecula Develops<\/strong><\/h3><p>Chronic UV radiation exposure initiates a cascade of cellular damage in the conjunctival tissue:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9b98db1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9b98db1\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-00203f9\" data-id=\"00203f9\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1619369 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"1619369\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2000\" height=\"660\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1.jpg\" class=\"attachment-full size-full wp-image-1189\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1.jpg 2000w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1-300x99.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1-1024x338.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1-768x253.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1-1536x507.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_Disease-Progression-Labeled-1-18x6.jpg 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-9026f4f\" data-id=\"9026f4f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9747f60 elementor-widget elementor-widget-text-editor\" data-id=\"9747f60\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>UV Exposure:<\/strong> DNA damage to conjunctival cells and limbal fibroblasts<\/p><p><strong>Cell Activation: <\/strong>\u00a0Upregulation of inflammatory cytokines (TNF-\u03b1, IL-6, IL-8)<\/p><p><strong>Growth Factor Release: <\/strong>\u00a0Overexpression of VEGF, PDGF, FGF, TGF-\u03b2<\/p><p><strong>Vascularization &amp; Fibrosis:<\/strong>\u00a0Abnormal fibrovascular deposit formation<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d207eba elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d207eba\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1a23ed7\" data-id=\"1a23ed7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-07101f1 elementor-widget elementor-widget-spacer\" data-id=\"07101f1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2746bd8 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"2746bd8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3><strong>How CBT-004 Intervenes<\/strong><\/h3><p>Because pinguecula involves multiple overlapping signaling pathways, <strong>single-target therapies are insufficient.<\/strong> When one pathway is blocked, others compensate \u2014 allowing disease to persist or progress. <strong>Cloudbreak&#8217;s MKI platform<\/strong> prevents this through <strong>simultaneous multi-pathway inhibition.<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-20b93f9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"20b93f9\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2e1c641\" data-id=\"2e1c641\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-41d782d elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"41d782d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2000\" height=\"660\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001.jpg\" class=\"attachment-full size-full wp-image-1270\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001.jpg 2000w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001-300x99.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001-1024x338.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001-768x253.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001-1536x507.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/newarc_ai_2-Disease-Progression-Labeled-Stacked-001-18x6.jpg 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f010201 elementor-widget elementor-widget-spacer\" data-id=\"f010201\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-20ac94d\" data-id=\"20ac94d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-46e470b elementor-widget elementor-widget-text-editor\" data-id=\"46e470b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: left;\"><strong>CBT-004 targets:<\/strong><\/p><p style=\"text-align: left;\"><strong>VEGFRs<\/strong>: Inhibits pathological angiogenesis\/vascularization<\/p><p style=\"text-align: left;\"><strong>PDGFRs<\/strong>: Reduces fibroblast activation and connective tissue remodeling<\/p><p style=\"text-align: left;\"><strong>FGFRs<\/strong>: Suppresses further inflammatory cell signaling<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d43774b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d43774b\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-549773c\" data-id=\"549773c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-785d9ef elementor-widget elementor-widget-spacer\" data-id=\"785d9ef\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dbcb79f elementor-widget elementor-widget-text-editor\" data-id=\"dbcb79f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><span style=\"color: #375e6f;\"><strong>CBT-004: Clinical Proof of Concept<\/strong><\/span><\/h2><h4 style=\"text-align: center;\">Phase 2 Results: Primary Endpoint Achieved. <br \/>First Pharmacologic Proof of Disease Modification in Pinguecula.<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3bed531 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3bed531\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-33895f6\" data-id=\"33895f6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-72d9de5\" data-id=\"72d9de5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c5e51c6 elementor-widget__width-initial uael-header-sticky-no uael-border-yes elementor-widget elementor-widget-uael-table\" data-id=\"c5e51c6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"uael-table.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div itemscope class=\"uael-table-wrapper\" itemtype=\"http:\/\/schema.org\/Table\">\n\t\t<table id=\"uael-table-id-c5e51c6\" class=\"uael-text-break uael-column-rules uael-table\" data-sort-table=\"no\" data-show-entry=\"no\" data-searchable=\"no\" data-responsive=\"no\">\n\t\t\t\t<thead>\n\t\t\t\t\t\t\t\t\t\t<tr class=\"uael-table-row\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<th data-sort=\"0\" class=\"sort-this elementor-repeater-item-10f3ba5 uael-table-col uael-table-head-cell-text\" scope=\"col\">\n\t\t\t\t\t\t\t<span class=\"sort-style\">\n\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">Treatment Group<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/th>\n\t\t\t\t\t\t\t\t\t\t\t\t<th data-sort=\"1\" class=\"sort-this elementor-repeater-item-838da8c uael-table-col uael-table-head-cell-text\" scope=\"col\">\n\t\t\t\t\t\t\t<span class=\"sort-style\">\n\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">Hyperemia Grade Change<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/th>\n\t\t\t\t\t\t\t\t\t\t\t\t<th data-sort=\"2\" class=\"sort-this elementor-repeater-item-3876cbf uael-table-col uael-table-head-cell-text\" scope=\"col\">\n\t\t\t\t\t\t\t<span class=\"sort-style\">\n\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">p-value vs Vehicle<\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/th>\n\t\t\t\t\t\t\t\t\t\t\t\t<th data-sort=\"3\" class=\"sort-this elementor-repeater-item-59aecd9 uael-table-col uael-table-head-cell-text\" scope=\"col\">\n\t\t\t\t\t\t\t<span class=\"sort-style\">\n\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\"><\/span>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t<\/th>\n\t\t\t\t\t\t\t\t<\/thead>\n\t\t\t\t<tbody>\n\t\t\t<!-- ROWS -->\n\t\t\t\t\t\t\t\t\t\t<tr data-entry=\"1\" class=\"uael-table-row\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-b2ea16c\" data-title=\"Treatment Group\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">Vehicle Control<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-26a2587\" data-title=\"Hyperemia Grade Change\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">0.30<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-a4cb005\" data-title=\"p-value vs Vehicle\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">---<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-aa255a2\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">N\/A<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr><tr data-entry=\"2\" class=\"uael-table-row\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-0366c30\" data-title=\"Treatment Group\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">CBT-004 0.05%<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-5a3734f\" data-title=\"Hyperemia Grade Change\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">-0.68<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-f662fd4\" data-title=\"p-value vs Vehicle\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">p = 0.043<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-1750436\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">Statistically significant<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/tr><tr data-entry=\"3\" class=\"uael-table-row\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-f71aa6c\" data-title=\"Treatment Group\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">CBT-004 0.075%<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-1483e4b\" data-title=\"Hyperemia Grade Change\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">-0.78<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-b2d0e04\" data-title=\"p-value vs Vehicle\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">p = 0.012<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<td class=\"uael-table-col uael-table-body-cell-text elementor-repeater-item-5bd2746\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"uael-table__text-inner\">Statistically significant<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/td>\n\t\t\t\t\t\t\t\t\t<\/tbody>\n\t<\/table>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-911cd93 elementor-widget elementor-widget-spacer\" data-id=\"911cd93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2039271 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"2039271\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2000\" height=\"807\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april.jpg\" class=\"attachment-full size-full wp-image-1368\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april.jpg 2000w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april-300x121.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april-1024x413.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april-768x310.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april-1536x620.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/04\/cb-004-hyperemia-chart-april-18x7.jpg 18w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-457b680\" data-id=\"457b680\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ef92e2c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ef92e2c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-60e50a0\" data-id=\"60e50a0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-47ec2dd elementor-widget elementor-widget-text-editor\" data-id=\"47ec2dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><span style=\"color: #375e6f;\"><strong> KEY CLINICAL HIGHLIGHTS<\/strong><\/span><\/h3>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e1a44d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e1a44d8\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-79c4262\" data-id=\"79c4262\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6ef7194 elementor-widget elementor-widget-image\" data-id=\"6ef7194\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"125\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg\" class=\"attachment-large size-large wp-image-1202\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-300x47.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-768x120.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1536x240.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-18x3.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ed93f7 elementor-widget elementor-widget-text-editor\" data-id=\"8ed93f7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 style=\"text-align: center;\">DOSE RESPONSE<\/h4><p style=\"text-align: center;\">Clear relationship observed between dose and efficacy (0.075% &gt; 0.05% &gt; vehicle) for hyperemia grade change<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-c88f405\" data-id=\"c88f405\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e16cca7 elementor-widget elementor-widget-image\" data-id=\"e16cca7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"125\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg\" class=\"attachment-large size-large wp-image-1202\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-300x47.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-768x120.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1536x240.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-18x3.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3416365 elementor-widget elementor-widget-text-editor\" data-id=\"3416365\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 id=\"irritation-or-foreign-body-sensation\" class=\"mb-2 mt-4 [.has-inline-images_&amp;]:clear-end font-sans visRefresh2026AnswerSerif:font-editorial font-semimedium visRefresh2026Fonts:font-bold text-base visRefresh2026Fonts:text-lg first:mt-0 md:text-lg [hr+&amp;]:mt-4\" style=\"text-align: center;\">EARLY ONSET<\/h4><p style=\"text-align: center;\">High dose showed a significant effect as early as Day 7 <br \/>(p = 0.007)\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-41c7388\" data-id=\"41c7388\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9817aff elementor-widget elementor-widget-image\" data-id=\"9817aff\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"125\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg\" class=\"attachment-large size-large wp-image-1202\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-300x47.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-768x120.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1536x240.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-18x3.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6015293 elementor-widget elementor-widget-text-editor\" data-id=\"6015293\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 style=\"text-align: center;\">CLEAR EFFICACY<\/h4><p style=\"text-align: center;\">Both doses superior to vehicle and are superior to current SOC options\u00a0\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-top-column elementor-element elementor-element-e43d19f\" data-id=\"e43d19f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8e629a8 elementor-widget elementor-widget-image\" data-id=\"8e629a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"125\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg\" class=\"attachment-large size-large wp-image-1202\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1024x160.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-300x47.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-768x120.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-1536x240.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar-18x3.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-1920-bar.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f4ed7cd elementor-widget elementor-widget-text-editor\" data-id=\"f4ed7cd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h4 style=\"text-align: center;\">WELL TOLERATED<\/h4><p style=\"text-align: center;\">No systemic\u00a0effects; mild &amp; transient local AEs only\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ed36df7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ed36df7\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bcc1191\" data-id=\"bcc1191\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dc70dde elementor-widget elementor-widget-text-editor\" data-id=\"dc70dde\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><span style=\"color: #ffffff;\">The time course data illustrates that <strong>CBT-004&#8217;s<\/strong> effects emerge rapidly and are sustained through the primary endpoint. The <strong>0.075% high-dose arm<\/strong> demonstrated a statistically significant separation from vehicle as early as <strong>Day 7 (p = 0.007)<\/strong> \u2014 a clinical indicator of <strong>rapid onset<\/strong> of pharmacological activity. Both doses continued to show <strong>significant benefit at Day 28,<\/strong> the primary endpoint. This early and sustained efficacy profile supports <strong>CBT-004&#8217;s<\/strong> potential as the first meaningful pharmacological therapy for vascularized pinguecula.<\/span><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-557788d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"557788d\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4fa09bf\" data-id=\"4fa09bf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9519f35 elementor-widget elementor-widget-spacer\" data-id=\"9519f35\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1ef11db elementor-widget elementor-widget-text-editor\" data-id=\"1ef11db\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><strong>PATIENT-REPORTED SYMPTOM: FOREIGN BODY SENSATION<\/strong><\/h3><h4 style=\"text-align: center;\">Primary Complaint from People with Pinguecula<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-af72b0e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"af72b0e\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-2e2f8ca\" data-id=\"2e2f8ca\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c903845 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"c903845\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\"><span class=\"s1\"><b>Why Measuring Both Hyperemia and Foreign Body Sensation (FBS) Matters Clinically:<\/b><b><\/b><\/span><\/p><p class=\"p1\"><span class=\"s1\">A treatment that reduces observable vascular pathology (hyperemia) without improving how patients feel (FBS and related symptoms) would offer limited real-world therapeutic value. Conversely, a treatment that only masks symptoms without addressing underlying disease mechanisms would not represent true disease modification.<\/span><\/p><p class=\"p1\"><span class=\"s1\"><b>CBT-004&#8217;s dual impact \u2014 on both objective vascular signs and subjective symptom burden \u2014 validates its potential as a comprehensive, disease-modifying therapy<\/b> that addresses the full spectrum of pinguecula pathology.<\/span><\/p><p class=\"p1\"><span class=\"s1\"><b>CBT-004 Phase 2 Results: Foreign Body Sensation (VAS Score, 0-100 Scale)<\/b><b><\/b><\/span><\/p><p class=\"p1\"><span class=\"s1\"><b>What Was Measured:<\/b> Foreign body sensation was assessed using a Visual Analog Scale (VAS) where patients rated their current level of grittiness\/discomfort on a <strong>0-100 scale (0 = no discomfort; 100 = worst imaginable discomfort)<\/strong>.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-c7d637b\" data-id=\"c7d637b\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6c5e2ab elementor-widget elementor-widget-image\" data-id=\"6c5e2ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"620\" height=\"750\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/FBS-Graphic.jpg\" class=\"attachment-large size-large wp-image-1218\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/FBS-Graphic.jpg 620w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/FBS-Graphic-248x300.jpg 248w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/FBS-Graphic-10x12.jpg 10w\" sizes=\"(max-width: 620px) 100vw, 620px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f2a02d2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f2a02d2\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b77175d\" data-id=\"b77175d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-abd0640 elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"abd0640\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"p1\"><span class=\"s1\"><b>Key Clinical Findings:<\/b><b><\/b><\/span><\/p><ol class=\"ol1\"><li class=\"li1\"><span class=\"s1\"><b>Rapid Onset of Symptom Relief:<\/b> Both CBT-004 doses showed statistically significant FBS improvement as early as Day 7 \u2014 within just one week of treatment initiation<\/span><\/li><li class=\"li1\"><span class=\"s1\"><b>Sustained Efficacy at Primary Endpoint:<\/b> At Day 28, both doses demonstrated clinically meaningful and statistically significant FBS reduction compared to vehicle<\/span><br \/><ul class=\"ul1\"><li class=\"li1\"><span class=\"s1\">0.05% dose: <b>-23.11 points<\/b> (p = 0.006) \u2014 represents ~56% improvement from baseline<\/span><\/li><li class=\"li1\"><span class=\"s1\">0.075% dose: <b>-18.76 points<\/b> (p = 0.045) \u2014 represents ~51% improvement from baseline<\/span><\/li><\/ul><\/li><li class=\"li1\"><span class=\"s1\"><b>Persistent Benefit During Follow-Up:<\/b> Even at Day 56 (4 weeks after treatment cessation), both doses maintained statistically significant symptom improvement, suggesting potential durability of effect<\/span><\/li><li class=\"li1\"><span class=\"s1\"><b>Consistency Across All Time Points:<\/b> FBS showed significant improvement at <b>every measured time point (Days 7, 28, and 56)<\/b> for <b>both doses<\/b> \u2014 one of the most consistent secondary endpoints in the study<\/span><\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4a86637 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4a86637\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e6037be\" data-id=\"e6037be\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-600ae19 elementor-widget elementor-widget-spacer\" data-id=\"600ae19\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-33048ab elementor-widget elementor-widget-text-editor\" data-id=\"33048ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><span style=\"color: #375e6f;\"><strong>Addressing a Critical Unmet Need<\/strong><\/span><\/h2><h4 style=\"text-align: center;\">More Than a Billion Patients Waiting for a Real Treatment<\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-13d961f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"13d961f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-5860e4e\" data-id=\"5860e4e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-af7a88c elementor-widget elementor-widget-image\" data-id=\"af7a88c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"534\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-1024x683.jpg\" class=\"attachment-large size-large wp-image-1204\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-1024x683.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-300x200.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-768x512.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-1536x1024.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe-18x12.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-globe.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-033cabb elementor-widget elementor-widget-text-editor\" data-id=\"033cabb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><strong>1+ Billion Affected<\/strong><\/h2><p style=\"text-align: center;\">Over 1 billion people globally <br \/>are affected by pinguecula<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-1005ac8\" data-id=\"1005ac8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19c1bfa elementor-widget elementor-widget-image\" data-id=\"19c1bfa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"534\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-1024x683.jpg\" class=\"attachment-large size-large wp-image-1149\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-1024x683.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-300x200.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-768x512.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-1536x1024.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink-18x12.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/cb-pt-nsaid-pink.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-58004d7 elementor-widget elementor-widget-text-editor\" data-id=\"58004d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><strong>No Treatments<\/strong><\/h2><p style=\"text-align: center;\">No FDA-approved drug therapies exist today<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-6c03d06\" data-id=\"6c03d06\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c1acb3a elementor-widget elementor-widget-image\" data-id=\"c1acb3a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"534\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-1024x684.jpg\" class=\"attachment-large size-large wp-image-1123\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-1024x684.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-300x200.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-768x513.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-1536x1025.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc-18x12.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/CB-ophthalmology-slit-lamp-exam-2026-01-05-23-03-51-utc.jpg 2000w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-57f0da0 elementor-widget elementor-widget-text-editor\" data-id=\"57f0da0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><strong>Phase 2 Complete<\/strong><\/h2><p style=\"text-align: center;\">CBT-004 has achieved first-in-class <br \/>proof-of-concept<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-f834643 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f834643\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b54adea\" data-id=\"b54adea\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-210aca6 elementor-widget elementor-widget-text-editor\" data-id=\"210aca6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h5><strong>Despite its enormous global prevalence, pinguecula has been historically neglected in ophthalmic drug development.<\/strong><\/h5><p>The condition sits in a <strong>therapeutic gap<\/strong>, considered by many providers as <strong>&#8220;not serious enough&#8221;<\/strong> for intervention, yet causing real daily symptoms that affect patients&#8217; comfort, vision quality, and quality of life. <strong>Eye care professionals currently lack<\/strong> any evidence-based, disease-modifying pharmacological tool to offer their patients.<\/p><p><strong>Cloudbreak&#8217;s CBT-004 changes that.<\/strong> For the first time, a clinically validated approach that directly targets the vascular and fibrotic changes driving pinguecula could be offered with a well-tolerated topical formulation that fits seamlessly into existing eye care workflows.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-81e154a elementor-widget elementor-widget-spacer\" data-id=\"81e154a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-605640d elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"605640d\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-66 elementor-top-column elementor-element elementor-element-fac17bd\" data-id=\"fac17bd\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aa925f4 elementor-widget elementor-widget-spacer\" data-id=\"aa925f4\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-92d293e elementor-widget__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"92d293e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2><span style=\"color: #ffffff;\"><strong>One Platform,<br \/>Multiple Conditions<\/strong><\/span><\/h2><h5>The same multi-kinase inhibitor mechanism that enables <strong>CBT-004&#8217;s<\/strong> activity in pinguecula positions Cloudbreak&#8217;s platform for broader application across anterior segment diseases characterized by abnormal fibrovascular activity. By targeting shared upstream signaling pathways \u2014 <strong>VEGF, PDGF, FGF, and TGF-\u03b2<\/strong> \u2014 the platform has potential utility in corneal neovascularization and other conditions where vascular and fibrotic dysregulation drives disease.<\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-d5ea37d\" data-id=\"d5ea37d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3b0dd74 elementor-widget elementor-widget-spacer\" data-id=\"3b0dd74\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2fe6f15 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"2fe6f15\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"800\" height=\"534\" src=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-1024x683.jpg\" class=\"attachment-large size-large wp-image-1226\" alt=\"\" srcset=\"https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-1024x683.jpg 1024w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-300x200.jpg 300w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-768x512.jpg 768w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-1536x1024.jpg 1536w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004-18x12.jpg 18w, https:\/\/cloudbreakpharma.com\/wp-content\/uploads\/2026\/02\/MKI-Graphic-Triad-004.jpg 1920w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cc515c6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cc515c6\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-623fd49\" data-id=\"623fd49\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-41804ed elementor-widget elementor-widget-spacer\" data-id=\"41804ed\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-72f00d1 elementor-widget elementor-widget-text-editor\" data-id=\"72f00d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h2 style=\"text-align: center;\"><span style=\"color: #ffffff;\"><strong>Why This Matters to People with Pinguecula,<br \/>Professionals &amp; Investors<\/strong><\/span><\/h2>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1bc07ad elementor-widget elementor-widget-text-editor\" data-id=\"1bc07ad\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"my-2 [&amp;+p]:mt-4 [&amp;_strong:has(+br)]:inline-block [&amp;_strong:has(+br)]:pb-2\"><span style=\"color: #ffffff;\">Pinguecula is a chronic, symptomatic ocular surface disease that can affect comfort, appearance, and daily functioning for millions of adults, it is more than a cosmetic concern. Framing pinguecula as a true disease state, rather than an incidental finding, highlights its impact on patients, the demands it places on clinical practice, and the broader burden on healthcare systems and payers.<\/span><\/p><p class=\"my-2 [&amp;+p]:mt-4 [&amp;_strong:has(+br)]:inline-block [&amp;_strong:has(+br)]:pb-2\"><span style=\"color: #ffffff;\">For patients, this means ongoing irritation, redness, and lifestyle limitations, often without a durable treatment option. For eye care professionals, it represents a frequent, recurring reason for visits that is managed largely with short-term symptomatic measures. For investors, the large, underserved patient population and lack of disease\u2011modifying therapies point to a meaningful opportunity for innovation.<\/span><\/p><p class=\"my-2 [&amp;+p]:mt-4 [&amp;_strong:has(+br)]:inline-block [&amp;_strong:has(+br)]:pb-2\"><span style=\"color: #ffffff;\">At Cloudbreak Pharma, we are advancing late\u2011stage drug candidates specifically designed to intervene earlier in this disease, with the goal of reducing symptoms, stabilizing the ocular surface, and ultimately decreasing the need for procedural or surgical interventions over time.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f91e988 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"f91e988\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-adfd046 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"adfd046\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-0aa800a\" data-id=\"0aa800a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6f2ab30 elementor-widget elementor-widget-text-editor\" data-id=\"6f2ab30\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><span style=\"color: #ffffff;\"><strong>People with Pinguecula<\/strong><\/span><\/h3>\n<p style=\"text-align: center;\"><span style=\"color: #ffffff;\">Find out more about the causes of pinguecula and current management options<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9e298dd elementor-align-center elementor-widget elementor-widget-button\" data-id=\"9e298dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn more<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-e3f6a09\" data-id=\"e3f6a09\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-90ca1f9 elementor-widget elementor-widget-text-editor\" data-id=\"90ca1f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><span style=\"color: #ffffff;\"><strong>Professionals<\/strong><\/span><\/h3>\n<p style=\"text-align: center;\"><span style=\"color: #ffffff;\">Find out how Multi-Kinase Inhibitors may represent the first disease modifying approach to treating pterygium<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f9dabb elementor-align-center elementor-widget elementor-widget-button\" data-id=\"5f9dabb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn more<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-33 elementor-top-column elementor-element elementor-element-f352817\" data-id=\"f352817\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0d61165 elementor-widget elementor-widget-text-editor\" data-id=\"0d61165\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<h3 style=\"text-align: center;\"><span style=\"color: #ffffff;\"><strong>Investors<\/strong><\/span><\/h3>\n<p style=\"text-align: center;\"><span style=\"color: #ffffff;\">Find out more about Cloudbreak Pharma as a potential investment opportunity on the Hong Kong Stock Exchange (2592.HK)<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7276533 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"7276533\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"#\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Learn more<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d728db1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d728db1\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9b3a884\" data-id=\"9b3a884\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>First Pharmacologic Approach to Target Pinguecula\u2019s Root Cause Cloudbreak Pharma is pioneering the first FDA-approvable pharmaceutical treatment for pinguecula \u2014 a condition affecting over 1 billion people worldwide with no approved pharmacological options. Our lead program, CBT-004, is a proprietary Multi-Kinase Inhibitor (MKI) eye drop designed to simultaneously target the multiple signaling pathways that drive [&hellip;]<\/p>\n","protected":false},"author":16,"featured_media":0,"parent":998,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1183","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Pinguecula Therapy - Cloudbreak Pharma, Inc.<\/title>\n<meta name=\"description\" content=\"Unmet needs in pterygium management? Learn more about the disease, current treatments, and explore the targeted therapeutic approach during trials\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cloudbreakpharma.com\/zh_hk\/our-focus\/pinguecula-therapy\/\" \/>\n<meta property=\"og:locale\" content=\"zh_HK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pinguecula Therapy - Cloudbreak Pharma, Inc.\" \/>\n<meta property=\"og:description\" content=\"Unmet needs in pterygium management? 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